Understanding atypical nuclear division of malaria parasites

Despite being key to rapid proliferation of malaria parasites in the human blood and other life cycle stages the mechanisms of cell division are still poorly understood. Our vision is to generate an extensive cell biological and genetic framework to dissect critical events during nuclear division. The study of this highly dynamic and small scale process requires exquisite temporal and spatial resolution. Hence, we are using a combination advanced imaging techniques such as live cell, super-resolution and correlative microscopy to study key structural elements of the division machinery. Thereby we hope to uncover new targets within this essential pathway and contribute to the fight against malaria.